TABLE II

Common Treatment Approaches Based on Tumor Subtype

Solid TumorsSensitivityCommonly Used Treatments*
Multiple myelomaHighly sensitiveLenalidomide, bortezomib, cyclophosphamide, steroids
Non-Hodgkin lymphomaHighly sensitiveCylcophosphamide, vincristine, adriamycin, etoposide, rituximab, steroids
Small-cell lung adenocarcinomaHighly sensitivePlatinum, etoposide
Breast adenocarcinomaSensitiveTaxanes, platinum, 5FU, epirubicin, antiestrogen, HER2 blockers
Non-small-cell lung adenocarcinomaRelatively sensitivePlatinum, pemetrexed, taxanes, TKIs, bevacizumab, nivolumab, pembrolizumab
SarcomaRelatively sensitiveAdriamycin, ifosfamide, taxanes, gemcitabine
Prostate adenocarcinomaRelatively sensitiveTaxanes, anti-androgens, abiraterone, enzalutamide
Thyroid adenocarcinomaRelatively sensitiveRadioactive iodine, TKIs
Renal-cell carcinomaResistantTKIs, mTOR inhibitors, nivolumab, cabozantinib
  • * 5FU = 5-fluorouracil, HER2 = human epidermal growth factor receptor 2, TKIs = tyrosine kinase inhibitors, and mTOR = mammalian target of rapamycin.